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Stevens–Johnson Syndrome & Toxic Epidermal Necrolysis

Stevens–Johnson Syndrome & Toxic Epidermal Necrolysis

What are Stevens–Johnson Syndrome & Toxic Epidermal Necrosis? Stevens-Johnson syndrome and toxic epidermal necrolysis are acute, potentially fatal, type IV hypersensitivity reactions where cytotoxic T cells inappropriately attack and kill epithelial cells in the mucosa and skin epidermis.